What is PFOA? Perfluorooctanoic acid (PFOA) is a man-made chemical used in various industrial and consumer applications since the 1950s. It is a member of the family of perfluoroalkyl substances (PFAS). A group of synthetic chemicals resistant to heat, water, and oil. PFOA is used to produce many everyday products. Such as non-stick cookware, stain-resistant carpets, and waterproof clothing. It ...